Pyrido-1,2-thiazines and their in vitro antibacterial evaluation.
نویسندگان
چکیده
A series of known and newly synthesized pyrido-1,2-thiazine derivatives of type 3-6 were evaluated against strains of Mycobacterium fortuitum (PCM 672) and Staphylococcus aureus (PCM 2602) The pilot experiments showed that most of the compounds in initial in vitro microbiological evaluation were not efficient antibacterial agents, but unexpectedly promoted replication of the microorganisms in the range of 10-50%.
منابع مشابه
Synthesis and studies on antibacterial activity of pyrido[3,2-e]-1,2-thiazines and related derivatives.
Twenty of the known and newly synthesized derivatives of pyrido-1,2-thiazine derivatives 3-7, which represent a novel class of potential antibacterial agents, were evaluated against strains of Mycobacterium fortuitum (PCM 672) and Staphylococcus aureus (PCM 2602). The pilot experiments showed that the compounds in an initial in vitro microbiological evaluation were not efficient antibacterial a...
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ورودعنوان ژورنال:
- Acta poloniae pharmaceutica
دوره 65 1 شماره
صفحات -
تاریخ انتشار 2008